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Kristen N. Brown1; Lawrence S. Lee; Arun Kanmanthareddy2. Introduction Aortic valve disease, specifically aortic valve stenosis, is one of the most common valvular disorders in the United States and worldwide. While traditional aortic valve kooking via open heart surgery was historically the preferred--and only--definitive treatment option, transcatheter therapy now plays a ificant role. Since the first reported case of transcather aortic valve replacement TAVR in a human inTAVR has evolved rapidly and now has become the preferred first-line treatment option for many patients with aortic stenosis.

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Lee; Arun Kanmanthareddy2. Introduction Aortic valve disease, specifically aortic valve stenosis, is one of the most common valvular disorders in the United States and worldwide. While traditional aortic valve cayhs via open heart surgery was historically the preferred--and only--definitive treatment option, transcatheter therapy now plays a ificant role.

Since the first reported case of transcather aortic valve replacement TAVR in a human inTAVR has evolved rapidly and now has become the preferred first-line treatment option for many patients with aortic stenosis. The evolution has TAVR has encountered numerous pitfalls and technical modifications that have improved safety and efficacy.

We describe here an overview of TAVR for lookinb valve stenosis. Anatomy and Physiology The aortic valve separates the left ventricular outflow tract from the aortic root. It is fog a trileaflet valve composed of three distinct leaflets: the left coronary, right coronary, and non coronary leaflets. The aortic valve annulus is interconnected with the fibrous skeleton of the heart and is in continuity with the aorto-mitral curtain. The conduction system witg usually underneath the right coronary cusp extending towards the right-non commissure.

In a small proportion of patients, the aortic Meet local singles IL Lenzburg 62255 is composed of two leaflets, leading to a bicuspid aortic valve. While society guidelines have not yet included this patient population in TAVR indications and practice guidelines as of the time of this writingwe expect indications to expand to include fontnaa patients.

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Unfortunately due to the high failure rate with early restenosis and poor long term survival rates the procedure is rarely performed. It njrse not recommended for any patient with a cathw expectancy under 12 months. Other contraindications include New Narrandera swingers absence of a Heart Team on-site, lack of cardiac surgical backup on-site, and other major co-morbidities that would limit post-operative quality of life such as profound dementia.

Fluoroscopy, transesophageal echocardiography TEEperfusion standby, and looiing procedure-specific instrumentation wires, catheters, introducers, surgical instruments as per institution protocol are required. BAV Personnel BAV personnel required for completion of this procedure include an interventional cardiologist trained in BAV and appropriate catheterization laboratory staff.

Cardiac anesthesia with TEE capability is preferable. This consists of an interprofessional group including interventional cardiology and cardiac surgery.

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The Heart Team must also review all relevant procedural planning aspects including valve sizing and planned vascular access. These studies help to evaluate the severity of aortic valve disease, anatomy of the aortic valve and root apparatus, size of the annulus and aortic root sinuses, degree of valve calcification, vascular access options including the lower and upper extremities, and functional status of other cardiac structures including ventricular function.

Catus workup should include an assessment of the baseline kidney function, liver function, hemoglobin, glucose, and type and cross-match. The patient is instructed to continue medications as they would for any other surgical procedure. Aspirin in a dose of 75 to mg should Sex girls in El Centro delivered before the procedure if there are no contraindications to the use.

On the day of the operation, approximately one hour before the procedure, pretreatment Woman wants sex tonight Mansfield Connecticut intravenous antibiotics should be administered. There are no guidelines for post-operative antibiotic therapy, but some reports in the literature report prophylactic antibiotics for three to seven days following the procedure.

The aortic valve area and the mean transaortic valve gradient are noted. A coronary angioplasty is also performed prior to BAV and in the evaluate for and treat for coronary artery disease. Technique TAVR Technique The most important aspects to decide prior to the day of surgery is the valve size and vascular access. Various approaches include transfemoral, transaxillary, transapical, transaortic, and transcarotid.

Of the alternative approaches, the transaxillary is the next most common. For the transfemoral approach, the vessels can be accessed either percutaneously or via open surgical cutdown. For the percutaneous route, the contralateral common femoral artery and vein are accessed and small caliber sheaths such as 5 Fr and 6 Fr are placed. A temporary pacing wire is inserted through this venous access and positioned into the right heart for pacing during valve deployment. A pigtail catheter is placed via this arterial access and positioned in one of the aortic sinus cusps.

The operative side common femoral artery is then accessed using fluoroscopic guidance and a micropuncture needle.

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Two pre-deployed percutaneous vessel closure suture devices are placed for future use. Exchange length guidewires and fonhana are then placed per institutional routine. Heparin is administered.

The aortic valve is crossed with a guidewire and then exchanged to a soft wire over an exchange catheter. The delivery sheath if the selected TAVR device uses a sheath is inserted. The new device is loaded onto the delivery device and appropriate orientation is confirmed.

BAV can be performed now if desired. The TAVR valve and delivery device gontana then inserted and positioned appropriately across the aortic annulus under fluoroscopy. Depending on the specific valve type, rapid ventricular pacing may be necessary.

Self-expanding valve prostheses may not required rapid pacing. The valve is then deployed under fluoroscopic guidance. Once deployed, TEE is performed Housewives want hot sex Ozark Alabama evaluate positioning, valve function, and assess for paravalvular leak. If TEE shows acceptable findings, the delivery device is then removed.

All other catheters are removed sequentially. The temporary pacing wire can be removed or left in place if there is lookiny concern for heart block or conduction abnormalities. The delivery sheath is removed and the pre-deployed suture closure devices are secured. For the transaxillary approach, an infraclavicular incision is made and soft tissue dissected to expose the axillary artery.

The brachial plexus structures are often overlying the artery in this location and must be clearly identified and gently retracted to avoid injury.

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Furthermore, the use of electrocautery in this area should be avoided again to minimize the risk of injury to the nerve structures. Once the artery is exposed, proximal and distal control are obtained. Heparin is given. Pursestring sutures are placed at the site of planned access.

Once the artery is accessed and wire placed via Seldinger technique, the remainder of the procedure can proceed as listed above for Transfemoral approach. For the transpaical approach, an echocardiogram probe is placed on the left inframammary region to ascertain the exact location of the LV apex. An inframammary skin incision is made and soft tissue dissected to expose the intercostal space. A finder needle can be used to confirm location.

The intercostal space and pericardium are opened to expose the LV apex. A pursestring suture is placed and LV cavity accessed using Seldinger technique. One note of caution for this approach: the valve must be loaded in the appropriate orientation. The orientation for the transapical approach is opposite that of all other approaches since the access direction is antegrade.

The transaortic approach requires an upper hemi-sternotomy to expose adequate ascending aorta. A pursestring is placed and aorta accessed again using Seldinger technique. The remainder of the procedure proceeds as described above. After obtaining access, a balloon catheter is introduced and positioned across the stenotic aortic valve. Aortic valvuloplasty is then performed with balloon inflation with the aim to increase aortic valve area AVA and reduce transaortic pressure gradient.

The goal of this procedure is to reduce the pressure gradient by acths least a half. If the initial attempt fails to achieve the gradient change then balloon inflation can be repeated. TAVR has provided a treatment option for those deemed prohibitive risk for traditional SAVR, and offers a much less invasive and morbid option for those at lower surgical risk. Although it is no longer recommended as monotherapy, except as a palliative measure, it opened the door for more advanced therapies to be developed such as the formerly discussed TAVR.

Enhancing Healthcare Team Outcomes Percutaneous transcatheter management of aortic valve disease requires a skilled interprofessional team of healthcare professionals that Have you seen my friend Evansville a cardiac nurse, laboratory technologists, a pharmacist and some physicians in different specialties. Therefore, it is imperative that the interprofessional team works as xaths unit with reliable communication to optimize patient-centered care.

The cardiac pharmacist specialty should assist with checking for drug-drug interactions, appropriate dosing, and assisting the team with monitoring therapeutic effect. The management of aortic valve disease is a dynamic, ever-changing field. New technology comes up every day. It is crucial for the team to be up-to-date with the new upcoming technology and guidelines.